Resumo de Description Of The Alzheimer Desease

The clinic manifestation of the Alzheimer desease (AD by after this initials in english) is a madness which begins typically with a loss of sutle memory and usually baldy accepted. The AD is the cause the most frequently of madness in North America and Europe, with four million individuals attacked estimate to United State. The prevalence of this desease inscease with the age. About 10 per cent of persons beyond of seventy years are a loss sinificiant of memory and most of half are the AD. The implication of not one environmental agent ( p.e cranial trauma, virus, toxins) haven?t been proved in the pathogenic of the AD. The familial case are the same clinic phenomen type and pathological that the sporadic.The genetic counsil is the action to apply to individuals and to families the informations on the nature, heredity and the consequences of genetic confusion so as to help them to take the personnal decisions and medical well informed. The genetic counsil for the persons Attack of the AD not familial must be empiric and unspecific. The people married of first degre of a person attack of the AD are a strong risk to develop the desease of fifteen and thirty per cent that which represent like a risk of twenty and twenty five per cent. A lot of individuals with a diagnosit AD advance establish are a person married attack, if the familial history is negative fourty per cent are attacked. The individuals with familial AD advance establish are apossibility of fifty per cent to transmit the mutant virus to each children. The treatment of the AD is inevitably pallative and each symdrom must be in charge of individual manner. In general, the individuals attacked to request a life assistance daily or the transfer in medical care center. Following the biochimical base ofthe AD is not well understood, we know that the deficit of cholinergic system and other neurotransmittor of brain are present.The medications which inscrease the cholinergic activity by inhibition of the acetylcholinesteasry induce a modest benefit but useful in a minority of individuals attacked. The first medication was the Tacrine. In the same time, this money is hepatotoxic. The news medications with a pharmacologic activity similar such as the Aricept (Donepezile), l?Exelon (Tivastigmine) or the Galantamine aren?t hepatotoxics. The rechearch on use AINS, steroids, neural factor of increasing and anti-oxydant are to be full evaluation.

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