Creatine Synthesis
(byJoseph F. Clark, Ph.D)
The cellular concentration of creatine is determined by the muscle's ability to take up creatine because muscle cannot make it. Creatine is synthesized in the liver and kidney and released into the blood stream to be actively taken up by the muscle cells. The liver plays a central role in the control of creatine in the body. The synthesis of creatine requires three amino acids; glycine, arginine, and methionine. The average synthesis of creatine by the body is 1-2 grams per day. A normal diet contains sufficient glycine, arginine, and methionine for the synthesis of creatine, but there is no evidence that supplementing these amino acids increases creatine synthesis
Resumos Relacionados
- Creatine Supplementation
- Creatine Supplementation And Water Balance
- Phosphocreatine
- Folic Acid
- Vitamin B-12
|
|