Resumo de Transoperatory Infusion Of Aminoacids And Glucose.

Transoperatory infusion of aminoacids and glucose.It's been described for almost 50 years that weight loss at thepreoperative period increases the postoperative mortality. Manyfactors, besides the malnutrition itself, contribute to this situation,for example, the patient illness, the surgical procedure, associatedinfections and others. It?s also known that in trauma, organic or not,there are disorders in proteic and aminoacid metabolism and an increaseon release of catabolic hormones. This study has the objective toevaluate if the endovenous infusion of a amino acid and glucosesolution, in a peripheric vein, in patients submitted to a surgicalprocedure, modifies the patients response to the trauma and/or thenitrogen retention. We studied 18 patients from the Surgery Division ofthe Clinical Hospital of the Federal University of Alagoas. The samemedical team followed all patients. After evaluation and consent of therealization of the study, they went on an assessment of the nutritionalstatus and were randomized in 2 groups. The group I (control group),during the perioperative period received a solution of lactate ringerand glucose 5%, as is usually done at this hospital. The group II (testgroup), besides the referred solution, received a mixture of aminoacids 6,6% and glucose 16,6%, meaning 50g of protein and 250g ofglucose during the transoperatory period. There was no statisticdifference between the groups studied in what concerns to age, sex,biochemistry tests, aminoacids and adrenalin urinary concentration atthe pre or postoperative periods. It has also been observed that groupII, that received a solution with aminoacid and glucose, hasn?texcreted more nitrogen through pre, trans and postoperative periods incomparation to group I, maintaining similar values of group I 24 hoursafter the anesthesic procedure. However, though group II had excretedsimilar values of nitrogen in comparation to group I, it had anitrogened balance less negative than group I (p<0,05) retainingapproximately 40% more aminoacidic nitrogen. From that, we concludethat the parenteral infusion of aminoacidic nitrogen 6,6% and glucose16,6% at the transoperative period may be a benefit to patients undersurgical stress.

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