Dna Mapping Success,promise
(p.naga prasad)
DNA mapping success,promise
Scientists have mapped patterns of tinyDNA differences that
distinguish one person from another. This willspeed upte
search for genes that promote common illness such as heart
disease and diabetes. Themap represents ?a realsea change
in how we study the genetics of disease,?said David
Altshler,a leader of the project that included more than
200 researchers from six natins. Scientists want to find
disease-related genes as a means to diagnose,predict and
devlop treatments. Such genes give clues to the biological
underpinnings of disease,and so suggest strategies to
devlop therapies. Genes that predispose people to common
disorders such as heart disease,cancer,diabetes,asthma and
others are devilishly hard tofind. But the new ?HapMap?-
taken from the genetics term,haplotype-opens the door to
launching comprehensive searches through the human DNA for
those genes,said Dr.Altshler. He does research at the
Board Insittute. The Harvard Institute of Technology,the
Massachusetts GeneralInstitute of Technology and
institute?s work. It is not yet clear how many genes will
be found or how useful theywill be,Dr.Altshuler said. The
achievement probably willnt result in new disease
treatments for five or 10 years or more,he said. HapMap
data have alreadybeen used totrack down a gene linked to
the eye disorder macular dgeneartin,said HapMapproject
participant Dr.Lincoln Stein of the Cold Spring Harbour
Laboratory in New York. The Map is described in Thursday?s
issue of the journal Nature. Participating scientists came
from Canada,china,japan,Nigeria,the U.K.and the U.S.The
Project analysed DNA samples form 269 people
fromNigeria,Beijing,Tokyo and Utah. Human DNA consists of
more than three billion building block spell a word. For
anytwo unrealated people,these letters are 99.9 per cent
the same. But the leaves millions of single-letter
differences,called SNPs (pronounced ?snips?)that provide
genetic variation between people. The HapMap shows how
more than a million of these SNPs form patterns:A person
with one particular versin of a SNP is highly likely to
carry particular versins aof other SNPs aas well.
Resumos Relacionados
- Genetic Engineering / Advantages And Disadvantages
- Women's Health
- Christian Perspectives On Cloning
- Gene Therapy For Rheumatoid Arthritis
- Vitamins For Anti Aging
|
|
