Resumo de Novel Drug Delivery System

The novel drug delivery system second edition is a
compilation of all important research carried out in the
field of drug delivery science till the date of its
publication in 1992.The book has twelve chapters where
first two is devoted to the most important aspect -- the
concepts of drug delivery and the latter ones explains in
great detail the scientific rationale as well as
technological aspects of specific delivery routes-
oral,parenteral,transdermal , nasal, intrauterine, vaginal
etc.

What is a Novel Drug Delivery System:?

Drugs are active substances which bind with the receptors
usually located deep within the body ? (to particular cells
or tissues) to alter the unwanted physiological process
that create disease. Sometimes the scientists come across
the right chemical or natural products that can bind to the
receptor and control an unwanted physiological process in
insolated tissue or cells but fail to reach the target
tissue in adequate quantity when administered in a
functioning living systems. Novel drug delivery is a vital
research area which strive to solve this problem and aim to
achieve a programmed delivery of the therapeutic
substances for the optimal beneficial effects while
avoiding the side effect of drugs.

How successful this research activity is?
This branch of pharmaceutical research involves
sophisticated technology and both animals and human life
and is a costly affair. Usually sponsored by industries,
who, to retrieve their investment often protect the
findings under patents. However publications in the
scientific journals are valuable source for information and
are discussed in detail by the author. It seems that in
many fields particularly sustained release oral delivery,
significant achievements have been done, many new products
are appearing in this area.

But the focus of future medicine will be biotechnological
where drug products are proteins. Since the protein drugs
get digested in gut, novel delivery route is a must for
their therapeutic application. Several microinjection
techniques and non-invasive transdermal route are getting
currently investigated for the same. The author, a
pioneering worker in the field of Transdermal Drug
Delivery has discussed the basic concepts of this high-
tech delivery mechanism iontophoresis ,sonophoresis ,
etc in great detail.

What is high point of the book?
The book clarifies some complicated concepts like feedback
regulation and Activation Modulated Drug Delivery with
clarity using examples that is of substantial help to the
pharmaceutical students.

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